Arsenic-Transformed Malignant Prostate Epithelia Can Convert Noncontiguous Normal Stem Cells into an Oncogenic Phenotype

Background: Cancer stem cells (CSCs) are likely critical to carcinogenesis, and, like normal stem cells (NSCs), are affected by microenvironmental factors. Malignant cells release extracellular factors, modifying tumor behavior. Inorganic arsenic, a human carcinogen, is associated with an overproduc...

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Bibliographic Details
Main Authors: Xu, Yuanyuan, Tokar, Erik J., Sun, Yang, Waalkes, Michael P.
Format: Online
Language:English
Published: National Institute of Environmental Health Sciences 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385457/