Regression of Atherosclerosis Is Characterized by Broad Changes in the Plaque Macrophage Transcriptome

We have developed a mouse model of atherosclerotic plaque regression in which an atherosclerotic aortic arch from a hyperlipidemic donor is transplanted into a normolipidemic recipient, resulting in rapid elimination of cholesterol and monocyte-derived macrophage cells (CD68+) from transplanted vess...

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Bibliographic Details
Main Authors: Feig, Jonathan E., Vengrenyuk, Yuliya, Reiser, Vladimir, Wu, Chaowei, Statnikov, Alexander, Aliferis, Constantin F., Garabedian, Michael J., Fisher, Edward A., Puig, Oscar
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384622/