Proneural Transcription Factors Regulate Different Steps of Cortical Neuron Migration through Rnd-Mediated Inhibition of RhoA Signaling

Little is known of the intracellular machinery that controls the motility of newborn neurons. We have previously shown that the proneural protein Neurog2 promotes the migration of nascent cortical neurons by inducing the expression of the atypical Rho GTPase Rnd2. Here, we show that another proneura...

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Bibliographic Details
Main Authors: Pacary, Emilie, Heng, Julian, Azzarelli, Roberta, Riou, Philippe, Castro, Diogo, Lebel-Potter, Mélanie, Parras, Carlos, Bell, Donald M., Ridley, Anne J., Parsons, Maddy, Guillemot, François
Format: Online
Language:English
Published: Cell Press 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383999/