Repeated injection of PEGylated solid lipid nanoparticles induces accelerated blood clearance in mice and beagles
Surface modification of nanocarriers with amphiphilic polymer polyethylene glycol (PEG), known as PEGylation, is regarded as a major breakthrough in the application of nanocarriers. However, PEGylated nanocarriers (including liposomes and polymeric nanoparticles) induce what is referred to as the “a...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Dove Medical Press
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383289/ |