Development of immune memory to glial brain tumors after tumor regression induced by immunotherapeutic Toll-like receptor 7/8 activation

Development of immune memory to glial brain tumors after tumor regression induced by immunotherapeutic Toll-like receptor 7/8 activation

The efficacy of immunotherapeutic TLR7/8 activation by resiquimod (R848) was evaluated in vivo, in the CNS-1 rat glioma model syngeneic to Lewis rats. The immune treatment was compared with cytotoxic cyclophosphamide chemotherapy, and as well, was compared with the combination cytotoxic and immunoth...

Full description

Bibliographic Details
Main Authors: Stathopoulos, Apostolis, Pretto, Chrystel, Devillers, Laurent, Pierre, Denis, Hofman, Florence M., Kruse, Carol, Jadus, Martin, Chen, Thomas C., Schijns, Virgil E.J.C.
Format: Online
Language:English
Published: Landes Bioscience 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382858/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382858/

Similar Items