Uric Acid Induces Renal Inflammation via Activating Tubular NF-κB Signaling Pathway

Inflammation is a pathologic feature of hyperuricemia in clinical settings. However, the underlying mechanism remains unknown. Here, infiltration of T cells and macrophages were significantly increased in hyperuricemia mice kidneys. This infiltration of inflammatory cells was accompanied by an up-re...

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Bibliographic Details
Main Authors: Zhou, Yang, Fang, Li, Jiang, Lei, Wen, Ping, Cao, Hongdi, He, Weichun, Dai, Chunsun, Yang, Junwei
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382585/