Optimized In Vivo Transfer of Small Interfering RNA Targeting Dermal Tissue Using In Vivo Surface Electroporation
Electroporation (EP) of mammalian tissue is a technique that has been used successfully in the clinic for the delivery of genetic-based vaccines in the form of DNA plasmids. There is great interest in platforms which efficiently deliver RNA molecules such as messenger RNA and small interfering RNA (...
Main Authors: | , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Nature Publishing Group
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381603/ |