Liver hyperplasia after tamoxifen induction of Myc in a transgenic medaka model

Myc is a global transcriptional regulator and one of the most frequently overexpressed oncoproteins in human tumors. It is well established that activation of Myc leads to enhanced cell proliferation but can also lead to increased apoptosis. The use of animal models expressing deregulated levels of...

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Bibliographic Details
Main Authors: Menescal, Luciana A., Schmidt, Cornelia, Liedtke, Daniel, Schartl, Manfred
Format: Online
Language:English
Published: The Company of Biologists Limited 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380712/