Methylation profiling of normal individuals reveals mosaic promoter methylation of cancer-associated genes
Epigenetic silencing by promoter methylation of genes associated with cancer initiation and progression is a hallmark of tumour cells. As a consequence, testing for DNA methylation biomarkers in plasma or other body fluids shows great promise for detection of malignancies at early stages and/or for...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Impact Journals LLC
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380579/ |