Deguelin Attenuates Reperfusion Injury and Improves Outcome after Orthotopic Lung Transplantation in the Rat

The main goal of adequate organ preservation is to avoid further cellular metabolism during the phase of ischemia. However, modern preservation solutions do rarely achieve this target. In donor organs hypoxia and ischemia induce a broad spectrum of pathologic molecular mechanisms favoring primary gr...

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Bibliographic Details
Main Authors: Paulus, Patrick, Ockelmann, Pia, Tacke, Sabine, Karnowski, Nora, Ellinghaus, Peter, Scheller, Bertram, Holfeld, Johannes, Urbschat, Anja, Zacharowski, Kai
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380011/