The chemotherapeutic drug oxaliplatin differentially affects blood DC function dependent on environmental cues

It has become evident that the tumor microenvironment plays a pivotal role in the maintenance of cancerous growth. One of the acquired functions of the tumor microenvironment is the suppression of immune responses. Indeed, blocking the inhibitory pathways operational in the microenvironment results...

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Bibliographic Details
Main Authors: Tel, Jurjen, Hato, Stanleyson V., Torensma, Ruurd, Buschow, Sonja I., Figdor, Carl G., Lesterhuis, W. Joost, de Vries, I. Jolanda M.
Format: Online
Language:English
Published: Springer-Verlag 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378839/