A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71
Enterovirus 71 (EV71), a major agent of hand-foot-and-mouth disease in children, can cause severe central nervous system disease and mortality. At present no vaccine or antiviral therapy is available. We have determined high-resolution structures for the mature virus and natural empty particles. The...
Main Authors: | , , , , , , , , , , , , , , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
2012
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378640/ |