TLR2, but Not TLR4, Is Required for Effective Host Defence against Chlamydia Respiratory Tract Infection in Early Life

Chlamydia pneumoniae commonly causes respiratory tract infections in children, and epidemiological investigations strongly link infection to the pathogenesis of asthma. The immune system in early life is immature and may not respond appropriately to pathogens. Toll-like receptor (TLR)2 and 4 are re...

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Bibliographic Details
Main Authors: Beckett, Emma L., Phipps, Simon, Starkey, Malcolm R., Horvat, Jay C., Beagley, Kenneth W., Foster, Paul S., Hansbro, Philip M.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378543/