DBIRD integrates alternative mRNA splicing with RNA polymerase II transcript elongation

DBIRD integrates alternative mRNA splicing with RNA polymerase II transcript elongation

Alternative mRNA splicing is the main reason vast mammalian proteomic complexity can be achieved with a limited number of genes. Splicing is physically and functionally coupled to transcription, and is greatly affected by the rate of transcript elongation1,2,3. As the nascent pre-mRNA emerges from t...

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Bibliographic Details
Main Authors: Close, Pierre, East, Philip, Dirac-Svejstrup, A. Barbara, Hartmann, Holger, Heron, Mark, Maslen, Sarah, Chariot, Alain, Söding, Johannes, Skehel, Mark, Svejstrup, Jesper Q.
Format: Online
Language:English
Published: 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378035/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378035/

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