Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine

Targeted cancer therapy requires the rapid and accurate identification of genetic abnormalities predictive of therapeutic response. We sought to develop a high-throughput genotyping platform that would allow prospective patient selection to the best available therapies, and that could readily and in...

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Bibliographic Details
Main Authors: Dias-Santagata, Dora, Akhavanfard, Sara, David, Serena S, Vernovsky, Kathy, Kuhlmann, Georgiana, Boisvert, Susan L, Stubbs, Hannah, McDermott, Ultan, Settleman, Jeffrey, Kwak, Eunice L, Clark, Jeffrey W, Isakoff, Steven J, Sequist, Lecia V, Engelman, Jeffrey A, Lynch, Thomas J, Haber, Daniel A, Louis, David N, Ellisen, Leif W, Borger, Darrell R, Iafrate, A John
Format: Online
Language:English
Published: WILEY-VCH Verlag 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377316/