Insulin biosynthesis in neuronal progenitors derived from adult hippocampus and the olfactory bulb

In the present study, we demonstrated that insulin is produced not only in the mammalian pancreas but also in adult neuronal cells derived from the hippocampus and olfactory bulb (OB). Paracrine Wnt3 plays an essential role in promoting the active expression of insulin in both hippocampal and OB-der...

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Bibliographic Details
Main Authors: Kuwabara, Tomoko, Kagalwala, Mohamedi N, Onuma, Yasuko, Ito, Yuzuru, Warashina, Masaki, Terashima, Kazuyuki, Sanosaka, Tsukasa, Nakashima, Kinichi, Gage, Fred H, Asashima, Makoto
Format: Online
Language:English
Published: WILEY-VCH Verlag 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377118/