Survivin the battle against immunosuppression
Improving on the limited success of cancer immunotherapy requires new approaches to inhibit immunosuppressive pathways initiated by tumor cells to “escape” protective immunity. One unique approach utilizes Salmonella for systemic delivery of inhibitory RNA, targeting the immunosuppressive molecule S...
| Main Authors: | , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Landes Bioscience
2012
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377007/ |
| id |
pubmed-3377007 |
|---|---|
| recordtype |
oai_dc |
| spelling |
pubmed-33770072012-06-20 Survivin the battle against immunosuppression Manuel, Edwin R. Blache, Céline A. Ellenhorn, Joshua D.I. Diamond, Don J. Author's View Improving on the limited success of cancer immunotherapy requires new approaches to inhibit immunosuppressive pathways initiated by tumor cells to “escape” protective immunity. One unique approach utilizes Salmonella for systemic delivery of inhibitory RNA, targeting the immunosuppressive molecule Stat3, and a Survivin vaccine to suppress growth of aggressive murine tumors. Landes Bioscience 2012-03-01 /pmc/articles/PMC3377007/ /pubmed/22720256 http://dx.doi.org/10.4161/onci.1.2.18180 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Manuel, Edwin R. Blache, Céline A. Ellenhorn, Joshua D.I. Diamond, Don J. |
| spellingShingle |
Manuel, Edwin R. Blache, Céline A. Ellenhorn, Joshua D.I. Diamond, Don J. Survivin the battle against immunosuppression |
| author_facet |
Manuel, Edwin R. Blache, Céline A. Ellenhorn, Joshua D.I. Diamond, Don J. |
| author_sort |
Manuel, Edwin R. |
| title |
Survivin the battle against immunosuppression |
| title_short |
Survivin the battle against immunosuppression |
| title_full |
Survivin the battle against immunosuppression |
| title_fullStr |
Survivin the battle against immunosuppression |
| title_full_unstemmed |
Survivin the battle against immunosuppression |
| title_sort |
survivin the battle against immunosuppression |
| description |
Improving on the limited success of cancer immunotherapy requires new approaches to inhibit immunosuppressive pathways initiated by tumor cells to “escape” protective immunity. One unique approach utilizes Salmonella for systemic delivery of inhibitory RNA, targeting the immunosuppressive molecule Stat3, and a Survivin vaccine to suppress growth of aggressive murine tumors. |
| publisher |
Landes Bioscience |
| publishDate |
2012 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377007/ |
| _version_ |
1611537349418680320 |