Solubilization and Humanization of Paraoxonase-1

Paraoxonase-1 (PON1) is a serum protein, the activity of which is related to susceptibility to cardiovascular disease and intoxication by organophosphorus (OP) compounds. It may also be involved in innate immunity, and it is a possible lead molecule in the development of a catalytic bioscavenger of...

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Bibliographic Details
Main Authors: Sarkar, Mohosin, Harsch, Christina Keventzidis, Matic, George T., Hoffman, Kathryn, Norris, Joseph R., Otto, Tamara C., Lenz, David E., Cerasoli, Douglas M., Magliery, Thomas J.
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376767/