Eps15R is required for bone morphogenetic protein signalling and differentially compartmentalizes with Smad proteins
Transforming growth factor β superfamily members signal through Smad transcription factors. Bone morphogenetic proteins (BMPs) act via Smads 1, 5 and 8 and TGF-βs signal through Smads 2 and 3. The endocytic adaptor protein Eps15R, or ‘epidermal growth factor (EGF) receptor pathway substrate 15-relat...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
The Royal Society
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376731/ |