Glutamine versus Ammonia Utilization in the NAD Synthetase Family

NAD is a ubiquitous and essential metabolic redox cofactor which also functions as a substrate in certain regulatory pathways. The last step of NAD synthesis is the ATP-dependent amidation of deamido-NAD by NAD synthetase (NADS). Members of the NADS family are present in nearly all species across th...

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Bibliographic Details
Main Authors: De Ingeniis, Jessica, Kazanov, Marat D., Shatalin, Konstantin, Gelfand, Mikhail S., Osterman, Andrei L., Sorci, Leonardo
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376133/