Identification of functional differences between recombinant human α and β cardiac myosin motors

The myosin isoform composition of the heart is dynamic in health and disease and has been shown to affect contractile velocity and force generation. While different mammalian species express different proportions of α and β myosin heavy chain, healthy human heart ventricles express these isoforms in...

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Bibliographic Details
Main Authors: Deacon, John C., Bloemink, Marieke J., Rezavandi, Heresh, Geeves, Michael A., Leinwand, Leslie A.
Format: Online
Language:English
Published: SP Birkhäuser Verlag Basel 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375423/