The Histone Demethylase Jhdm1a Regulates Hepatic Gluconeogenesis

Hepatic gluconeogenesis is required for maintaining blood glucose homeostasis; yet, in diabetes mellitus, this process is unrestrained and is a major contributor to fasting hyperglycemia. To date, the impacts of chromatin modifying enzymes and chromatin landscape on gluconeogenesis are poorly unders...

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Bibliographic Details
Main Authors: Pan, Dongning, Mao, Chunxiao, Zou, Tie, Yao, Annie Y., Cooper, Marcus P., Boyartchuk, Victor, Wang, Yong-Xu
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375226/