Association of Base Excision Repair Gene Polymorphisms with ESRD Risk in a Chinese Population
The base excision repair (BER) pathway, containing OGG1, MTH1 and MUTYH, is a major protector from oxidative DNA damage in humans, while 8-oxoguanine (8-OHdG), an index of DNA oxidation, is increased in maintenance hemodialysis (HD) patients. Four polymorphisms of BER genes, OGG1 c.977C > G (rs10...
Main Authors: | , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Hindawi Publishing Corporation
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375099/ |