Detection of allele-specific methylation through a generalized heterogeneous epigenome model
Motivations: High-throughput sequencing has made it possible to sequence DNA methylation of a whole genome at the single-base resolution. A sample, however, may contain a number of distinct methylation patterns. For instance, cells of different types and in different developmental stages may have di...
Main Authors: | , |
---|---|
Format: | Online |
Language: | English |
Published: |
Oxford University Press
2012
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371863/ |