A single source k-shortest paths algorithm to infer regulatory pathways in a gene network

Motivation: Inferring the underlying regulatory pathways within a gene interaction network is a fundamental problem in Systems Biology to help understand the complex interactions and the regulation and flow of information within a system-of-interest. Given a weighted gene network and a gene in this...

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Bibliographic Details
Main Authors: Shih, Yu-Keng, Parthasarathy, Srinivasan
Format: Online
Language:English
Published: Oxford University Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371844/