Zbtb46 expression distinguishes classical dendritic cells and their committed progenitors from other immune lineages

The zinc finger transcription factor Zbtb46 specifically marks cDCs and their committed precursors and, when overexpressed in BM progenitors, promotes cDC development at the expense of granulocytes.

Bibliographic Details
Main Authors: Satpathy, Ansuman T., KC, Wumesh, Albring, Jörn C., Edelson, Brian T., Kretzer, Nicole M., Bhattacharya, Deepta, Murphy, Theresa L., Murphy, Kenneth M.
Format: Online
Language:English
Published: The Rockefeller University Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371733/