Surgical Resection for Small Cell Lung Cancer: Pneumonectomy versus Lobectomy
Background. There are some patients with SCLC that are diagnosed in the operating room by cryosection and surgeons had to perform surgical resection for these patients. The aim of this study is to compare the effective of pneumonectomy with lobectomy for SCLC. Methods. A retrospective study was un...
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International Scholarly Research Network
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369481/ |
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pubmed-33694812012-06-13 Surgical Resection for Small Cell Lung Cancer: Pneumonectomy versus Lobectomy Yuequan, Jiang Zhi, Zhang Chenmin, Xie Clinical Study Background. There are some patients with SCLC that are diagnosed in the operating room by cryosection and surgeons had to perform surgical resection for these patients. The aim of this study is to compare the effective of pneumonectomy with lobectomy for SCLC. Methods. A retrospective study was undertaken in 75 patients with SCLC that were diagnosed by cryosection during surgery. 31 of them underwent pneumonectomy, 44 underwent lobectomy. Local recurrence rate and survival rate according to surgical procedures and cancer stages were analyzed. Results. There was significant difference in the overall survival rate between lobectomy and pneumonectomy groups (P = 0.044). For patients with stage II SCLC, the overall survival rate after pneumonectomy was significantly better than after lobectomy (P = 0.028). No significant difference in overall survival rate was found between the two surgical groups in patients with stage III SCLC (P = 0.933). The local recurrence rate in lobectomy group was significant higher that in pneumonectomy group (P = 0.0017). Conclusions. SCLC was responsive to surgical therapy. When surgeons have to select an appropriate method of operation for patients with SCLC during surgery, pneumonectomy may be the right choice for these patients. Pneumonectomy can result in significantly better local control and higher survival rate compare with lobectomy. International Scholarly Research Network 2012-05-30 /pmc/articles/PMC3369481/ /pubmed/22701187 http://dx.doi.org/10.5402/2012/101024 Text en Copyright © 2012 Jiang Yuequan et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Yuequan, Jiang Zhi, Zhang Chenmin, Xie |
| spellingShingle |
Yuequan, Jiang Zhi, Zhang Chenmin, Xie Surgical Resection for Small Cell Lung Cancer: Pneumonectomy versus Lobectomy |
| author_facet |
Yuequan, Jiang Zhi, Zhang Chenmin, Xie |
| author_sort |
Yuequan, Jiang |
| title |
Surgical Resection for Small Cell Lung Cancer: Pneumonectomy versus Lobectomy |
| title_short |
Surgical Resection for Small Cell Lung Cancer: Pneumonectomy versus Lobectomy |
| title_full |
Surgical Resection for Small Cell Lung Cancer: Pneumonectomy versus Lobectomy |
| title_fullStr |
Surgical Resection for Small Cell Lung Cancer: Pneumonectomy versus Lobectomy |
| title_full_unstemmed |
Surgical Resection for Small Cell Lung Cancer: Pneumonectomy versus Lobectomy |
| title_sort |
surgical resection for small cell lung cancer: pneumonectomy versus lobectomy |
| description |
Background. There are some patients with SCLC that are diagnosed in the operating room by cryosection and surgeons had to perform surgical resection for these patients. The aim of this study is to compare the effective of pneumonectomy with lobectomy for SCLC.
Methods. A retrospective study was undertaken in 75 patients with SCLC that were diagnosed by cryosection during surgery. 31 of them underwent pneumonectomy, 44 underwent lobectomy. Local recurrence rate and survival rate according to surgical procedures and cancer stages were analyzed. Results. There was significant difference in the overall survival rate between lobectomy and pneumonectomy groups (P = 0.044). For patients with stage II SCLC, the overall survival rate after pneumonectomy was significantly better than after lobectomy (P = 0.028). No significant difference in overall survival rate was found between the two surgical groups in patients with stage III SCLC (P = 0.933). The local recurrence rate in lobectomy group was significant higher that in pneumonectomy group (P = 0.0017). Conclusions. SCLC was responsive to surgical therapy. When surgeons have to select an appropriate method of operation for patients with SCLC during surgery, pneumonectomy may be the right choice for these patients. Pneumonectomy can result in significantly better local control and higher survival rate compare with lobectomy.
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| publisher |
International Scholarly Research Network |
| publishDate |
2012 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369481/ |
| _version_ |
1611535223189667840 |