Employment of gene expression profiling to identify transcriptional regulators of hepatic stellate cells

Activated hepatic stellate cells (HSC) play a central role in scar formation that leads to liver fibrosis. The molecular mechanisms underlying this process are not fully understood. Microarray and bioinformatics analyses have proven to be useful in identifying transcription factors that regulate cel...

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Bibliographic Details
Main Authors: Shimada, Hideaki, Rajagopalan, Lakshman E
Format: Online
Language:English
Published: BioMed Central 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368757/