Sequence dependence of isothermal DNA amplification via EXPAR

Isothermal nucleic acid amplification is becoming increasingly important for molecular diagnostics. Therefore, new computational tools are needed to facilitate assay design. In the isothermal EXPonential Amplification Reaction (EXPAR), template sequences with similar thermodynamic characteristics pe...

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Bibliographic Details
Main Authors: Qian, Jifeng, Ferguson, Tanya M., Shinde, Deepali N., Ramírez-Borrero, Alissa J., Hintze, Arend, Adami, Christoph, Niemz, Angelika
Format: Online
Language:English
Published: Oxford University Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367216/