DNA looping by FokI: the impact of twisting and bending rigidity on protein-induced looping dynamics

Protein-induced DNA looping is crucial for many genetic processes such as transcription, gene regulation and DNA replication. Here, we use tethered-particle motion to examine the impact of DNA bending and twisting rigidity on loop capture and release, using the restriction endonuclease FokI as a tes...

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Bibliographic Details
Main Authors: Laurens, Niels, Rusling, David A., Pernstich, Christian, Brouwer, Ineke, Halford, Stephen E., Wuite, Gijs J. L.
Format: Online
Language:English
Published: Oxford University Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367208/