A Pilot Study Assessing the Potential Role of non-CD133 Colorectal Cancer Stem Cells as Biomarkers

Introduction: Over 50% of patients with colorectal cancer (CRC) will progress and/or develop metastases. Biomarkers capable of predicting progression, risk stratification and therapeutic benefit are needed. Cancer stem cells are thought to be responsible for tumor initiation, dissemination and treat...

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Main Authors:	Langan, Russell C., Mullinax, John E., Ray, Satyajit, Raiji, Manish T., Schaub, Nicholas, Xin, Hong-Wu, Koizumi, Tomotake, Steinberg, Seth M., Anderson, Andrew, Wiegand, Gordon, Butcher, Donna, Anver, Miriam, Bilchik, Anton J., Stojadinovic, Alexander, Rudloff, Udo, Avital, Itzhak
Format:	Online
Language:	English
Published:	Ivyspring International Publisher 2012
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366478/

id	pubmed-3366478
recordtype	oai_dc
spelling	pubmed-33664782012-06-05 A Pilot Study Assessing the Potential Role of non-CD133 Colorectal Cancer Stem Cells as Biomarkers Langan, Russell C. Mullinax, John E. Ray, Satyajit Raiji, Manish T. Schaub, Nicholas Xin, Hong-Wu Koizumi, Tomotake Steinberg, Seth M. Anderson, Andrew Wiegand, Gordon Butcher, Donna Anver, Miriam Bilchik, Anton J. Stojadinovic, Alexander Rudloff, Udo Avital, Itzhak Research Paper Introduction: Over 50% of patients with colorectal cancer (CRC) will progress and/or develop metastases. Biomarkers capable of predicting progression, risk stratification and therapeutic benefit are needed. Cancer stem cells are thought to be responsible for tumor initiation, dissemination and treatment failure. Therefore, we hypothesized that CRC cancer stem cell markers (CRCSC) will identify a group of patients at high risk for progression. Ivyspring International Publisher 2012-06-01 /pmc/articles/PMC3366478/ /pubmed/22670157 http://dx.doi.org/10.7150/jca.4542 Text en © Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Langan, Russell C. Mullinax, John E. Ray, Satyajit Raiji, Manish T. Schaub, Nicholas Xin, Hong-Wu Koizumi, Tomotake Steinberg, Seth M. Anderson, Andrew Wiegand, Gordon Butcher, Donna Anver, Miriam Bilchik, Anton J. Stojadinovic, Alexander Rudloff, Udo Avital, Itzhak
spellingShingle	Langan, Russell C. Mullinax, John E. Ray, Satyajit Raiji, Manish T. Schaub, Nicholas Xin, Hong-Wu Koizumi, Tomotake Steinberg, Seth M. Anderson, Andrew Wiegand, Gordon Butcher, Donna Anver, Miriam Bilchik, Anton J. Stojadinovic, Alexander Rudloff, Udo Avital, Itzhak A Pilot Study Assessing the Potential Role of non-CD133 Colorectal Cancer Stem Cells as Biomarkers
author_facet	Langan, Russell C. Mullinax, John E. Ray, Satyajit Raiji, Manish T. Schaub, Nicholas Xin, Hong-Wu Koizumi, Tomotake Steinberg, Seth M. Anderson, Andrew Wiegand, Gordon Butcher, Donna Anver, Miriam Bilchik, Anton J. Stojadinovic, Alexander Rudloff, Udo Avital, Itzhak
author_sort	Langan, Russell C.
title	A Pilot Study Assessing the Potential Role of non-CD133 Colorectal Cancer Stem Cells as Biomarkers
title_short	A Pilot Study Assessing the Potential Role of non-CD133 Colorectal Cancer Stem Cells as Biomarkers
title_full	A Pilot Study Assessing the Potential Role of non-CD133 Colorectal Cancer Stem Cells as Biomarkers
title_fullStr	A Pilot Study Assessing the Potential Role of non-CD133 Colorectal Cancer Stem Cells as Biomarkers
title_full_unstemmed	A Pilot Study Assessing the Potential Role of non-CD133 Colorectal Cancer Stem Cells as Biomarkers
title_sort	pilot study assessing the potential role of non-cd133 colorectal cancer stem cells as biomarkers
description	Introduction: Over 50% of patients with colorectal cancer (CRC) will progress and/or develop metastases. Biomarkers capable of predicting progression, risk stratification and therapeutic benefit are needed. Cancer stem cells are thought to be responsible for tumor initiation, dissemination and treatment failure. Therefore, we hypothesized that CRC cancer stem cell markers (CRCSC) will identify a group of patients at high risk for progression.
publisher	Ivyspring International Publisher
publishDate	2012
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366478/
_version_	1611534410101817344

A Pilot Study Assessing the Potential Role of non-CD133 Colorectal Cancer Stem Cells as Biomarkers

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