Modulation of microRNA Activity by Semi-microRNAs

The ribonuclease Dicer plays a central role in the microRNA pathway by catalyzing the formation of 19–24-nucleotide (nt) long microRNAs. Subsequently incorporated into Argonaute 2 (Ago2) effector complexes, microRNAs are known to regulate messenger RNA (mRNA) translation. Whether shorter RNA species...

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Bibliographic Details
Main Authors: Plante, Isabelle, Plé, Hélène, Landry, Patricia, Gunaratne, Preethi H., Provost, Patrick
Format: Online
Language:English
Published: Frontiers Research Foundation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366366/