BRCA1 Regulates Follistatin Function in Ovarian Cancer and Human Ovarian Surface Epithelial Cells

Follistatin (FST), a folliculogenesis regulating protein, is found in relatively high concentrations in female ovarian tissues. FST acts as an antagonist to Activin, which is often elevated in human ovarian carcinoma, and thus may serve as a potential target for therapeutic intervention against ovar...

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Bibliographic Details
Main Authors: Karve, Tejaswita M., Preet, Anju, Sneed, Rosie, Salamanca, Clara, Li, Xin, Xu, Jingwen, Kumar, Deepak, Rosen, Eliot M., Saha, Tapas
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365892/