Talin activates integrins by altering the topology of the β transmembrane domain

Talin binding to the integrin β tail alters the β transmembrane domain’s topology, resulting in integrin activation.

Bibliographic Details
Main Authors: Kim, Chungho, Ye, Feng, Hu, Xiaohui, Ginsberg, Mark H.
Format: Online
Language:English
Published: The Rockefeller University Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365499/