Modes of Retrotransposition of Long Interspersed Element-1 by Environmental Factors

Approximately 42% of the human genome is composed of endogenous retroelements, and the major retroelement component, long interspersed element-1 (L1), comprises ∼17% of the total genome. A single human cell has more than 5 × 105 copies of L1, 80∼100 copies of which are competent for retrotranspositi...

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Bibliographic Details
Main Authors: Ishizaka, Yukihito, Okudaira, Noriyuki, Tamura, Masato, Iijima, Kenta, Shimura, Mari, Goto, Motohito, Okamura, Tadashi
Format: Online
Language:English
Published: Frontiers Research Foundation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364524/