Conformational epitopes at cadherin calcium-binding sites and p120-catenin phosphorylation regulate cell adhesion
The activity state of E-cadherin is controlled by conformational epitopes at interfaces between different EC domains, which are coupled to p120-catenin phosphorylation. Dephosphorylation activates adhesion, whereas phosphorylation inhibits activation. p120-dependent changes in the physical state of...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
The American Society for Cell Biology
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364174/ |