Hypoxia-inducible factor 1 protects hypoxic astrocytes against glutamate toxicity
Stroke is a major neurological disorder characterized by an increase in the Glu (glutamate) concentration resulting in excitotoxicity and eventually cellular damage and death in the brain. HIF-1 (hypoxia-inducible factor-1), a transcription factor, plays an important protective role in promoting cel...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
American Society for Neurochemistry
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3363983/ |