Inference of Tumor Phylogenies from Genomic Assays on Heterogeneous Samples

Tumorigenesis can in principle result from many combinations of mutations, but only a few roughly equivalent sequences of mutations, or “progression pathways,” seem to account for most human tumors. Phylogenetics provides a promising way to identify common progression pathways and markers of those...

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Bibliographic Details
Main Authors: Subramanian, Ayshwarya, Shackney, Stanley, Schwartz, Russell
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359715/