Inference of Tumor Phylogenies from Genomic Assays on Heterogeneous Samples
Tumorigenesis can in principle result from many combinations of mutations, but only a few roughly equivalent sequences of mutations, or “progression pathways,” seem to account for most human tumors. Phylogenetics provides a promising way to identify common progression pathways and markers of those...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
Hindawi Publishing Corporation
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359715/ |