In Vivo Evolution of Tumor-Derived Endothelial Cells

The growth of a malignant tumor beyond a certain, limited size requires that it first develop an independent blood supply. In addition to providing metabolic support, this neovasculature also allows tumor cells to access the systemic circulation, thus facilitating metastatic dissemination. The neova...

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Bibliographic Details
Main Authors: McGuire, Terence F., Sajithlal, Gangadharan B., Lu, Jie, Nicholls, Robert D., Prochownik, Edward V.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356387/