Memory Immune Responses against Pandemic (H1N1) 2009 Influenza Virus Induced by a Whole Particle Vaccine in Cynomolgus Monkeys Carrying Mafa-A1*052∶02

We made an H1N1 vaccine candidate from a virus library consisting of 144 ( = 16 HA×9 NA) non-pathogenic influenza A viruses and examined its protective effects against a pandemic (2009) H1N1 strain using immunologically naïve cynomolgus macaques to exclude preexisting immunity and to employ a precli...

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Bibliographic Details
Main Authors: Arikata, Masahiko, Itoh, Yasushi, Okamatsu, Masatoshi, Maeda, Toshinaga, Shiina, Takashi, Tanaka, Keiko, Suzuki, Shingo, Nakayama, Misako, Sakoda, Yoshihiro, Ishigaki, Hirohito, Takada, Ayato, Ishida, Hideaki, Soda, Kosuke, Pham, Van Loi, Tsuchiya, Hideaki, Nakamura, Shinichiro, Torii, Ryuzo, Shimizu, Takeshi, Inoko, Hidetoshi, Ohkubo, Iwao, Kida, Hiroshi, Ogasawara, Kazumasa
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356377/