Coseeded Schwann cells myelinate neurites from differentiated neural stem cells in neurotrophin-3-loaded PLGA carriers

Biomaterials and neurotrophic factors represent promising guidance for neural repair. In this study, we combined poly-(lactic acid-co-glycolic acid) (PLGA) conduits and neurotrophin-3 (NT-3) to generate NT-3-loaded PLGA carriers in vitro. Bioactive NT-3 was released stably and constantly from PLGA c...

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Bibliographic Details
Main Authors: Xiong, Yi, Zhu, Ji-Xiang, Fang, Zheng-Yu, Zeng, Cheng-Guang, Zhang, Chao, Qi, Guo-Long, Li, Man-Hui, Zhang, Wei, Quan, Da-Ping, Wan, Jun
Format: Online
Language:English
Published: Dove Medical Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356173/