An evaluation of different meta-analysis approaches in the presence of allelic heterogeneity

Meta-analysis has proven a useful tool in genetic association studies. Allelic heterogeneity can arise from ethnic background differences across populations being meta-analyzed (for example, in search of common frequency variants through genome-wide association studies), and through the presence of...

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Bibliographic Details
Main Authors: Asimit, Jennifer, Day-Williams, Aaron, Zgaga, Lina, Rudan, Igor, Boraska, Vesna, Zeggini, Eleftheria
Format: Online
Language:English
Published: Nature Publishing Group 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355266/