Functions of Protosilencers in the Formation and Maintenance of Heterochromatin in Saccharomyces cerevisiae

In Saccharomyces cerevisiae, transcriptionally silent heterochromatin at HML and HMR loci is established by silencers that recruit SIR complex and promote its propagation along chromatin. Silencers consist of various combinations of two or three binding sites for origin recognition complex (ORC), Ab...

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Bibliographic Details
Main Authors: Zhang, Xinmin, Yu, Qun, Olsen, Lars, Bi, Xin
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355138/