Enzymatic Activities and DNA Substrate Specificity of Mycobacterium tuberculosis DNA Helicase XPB

XPB, also known as ERCC3 and RAD25, is a 3′→5′ DNA repair helicase belonging to the superfamily 2 of helicases. XPB is an essential core subunit of the eukaryotic basal transcription factor complex TFIIH. It has two well-established functions: in the context of damaged DNA, XPB facilitates nucleotid...

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Bibliographic Details
Main Authors: Balasingham, Seetha V., Zegeye, Ephrem Debebe, Homberset, Håvard, Rossi, Marie L., Laerdahl, Jon K., Bohr, Vilhelm A., Tønjum, Tone
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353954/