Tautomerism in 11-Hydroxyaklavinone: A DFT Study

The antharquinone-based chromophore of 11-hydroxyaklavinone is present in the structure of an anticancer agent, daunomycin. On the other hand, aklavinone is the parent aglycone of certain anthracycline antibiotics that possess anti-cancer activity too. The structures of aklavinone and its 11-hydroxy...

Full description

Bibliographic Details
Main Author: Türker, Lemi
Format: Online
Language:English
Published: The Scientific World Journal 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353482/