A novel phage-encoded transcription antiterminator acts by suppressing bacterial RNA polymerase pausing

A novel phage-encoded transcription antiterminator acts by suppressing bacterial RNA polymerase pausing

Gp39, a small protein encoded by Thermus thermophilus phage P23–45, specifically binds the host RNA polymerase (RNAP) and inhibits transcription initiation. Here, we demonstrate that gp39 also acts as an antiterminator during transcription through intrinsic terminators. The antitermination activity...

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Bibliographic Details
Main Authors: Berdygulova, Zhanna, Esyunina, Daria, Miropolskaya, Nataliya, Mukhamedyarov, Damir, Kuznedelov, Konstantin, Nickels, Bryce E., Severinov, Konstantin, Kulbachinskiy, Andrey, Minakhin, Leonid
Format: Online
Language:English
Published: Oxford University Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351154/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351154/

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