Factors Determining Sensitivity and Resistance of Tumor Cells to Arsenic Trioxide

Previously, arsenic trioxide showed impressive regression rates of acute promyelocytic leukemia. Here, we investigated molecular determinants of sensitivity and resistance of cell lines of different tumor types towards arsenic trioxide. Arsenic trioxide was the most cytotoxic compound among 8 arseni...

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Bibliographic Details
Main Authors: Sertel, Serkan, Tome, Margaret, Briehl, Margaret M., Bauer, Judith, Hock, Kai, Plinkert, Peter K., Efferth, Thomas
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349672/