Dll4–Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice

Blocking Dll4–Notch signaling can reverse established diabetes via Flt3-independent induction of immature thymic DCs that enhance Treg cell generation in mice.

Bibliographic Details
Main Authors: Billiard, Fabienne, Lobry, Camille, Darrasse-Jèze, Guillaume, Waite, Janelle, Liu, Xia, Mouquet, Hugo, DaNave, Amanda, Tait, Michelle, Idoyaga, Juliana, Leboeuf, Marylène, Kyratsous, Christos A., Burton, Jacquelynn, Kalter, Julie, Klinakis, Apostolos, Zhang, Wen, Thurston, Gavin, Merad, Miriam, Steinman, Ralph M., Murphy, Andrew J., Yancopoulos, George D., Aifantis, Iannis, Skokos, Dimitris
Format: Online
Language:English
Published: The Rockefeller University Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348095/