The Role of p66shc in Oxidative Stress and Apoptosis
p66shcis a gene that regulates the level of reactive oxygen species (ROS), apoptosis induction, and lifespan in mammals. Miceknocked out forp66shchave a lifespan~30% longeranddemonstrate an enhanced resistance to oxidative stress and age-related pathologies such as hypercholesterolemia, ischemia, a...
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| Format: | Online |
| Language: | English |
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A.I. Gordeyev
2010
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347587/ |