Activation of the Dormant Secondary Metabolite Production by Introducing Gentamicin-Resistance in a Marine-Derived Penicillium purpurogenum G59

Activation of the Dormant Secondary Metabolite Production by Introducing Gentamicin-Resistance in a Marine-Derived Penicillium purpurogenum G59

A new approach to activate silent gene clusters for dormant secondary metabolite production has been developed by introducing gentamicin-resistance to an originally inactive, marine-derived fungal strain Penicillium purpurogenum G59. Upon treatment of the G59 spores with a high concentration of gent...

Full description

Bibliographic Details
Main Authors:	Chai, Yun-Jing, Cui, Cheng-Bin, Li, Chang-Wei, Wu, Chang-Jing, Tian, Cong-Kui, Hua, Wei
Format:	Online
Language:	English
Published:	MDPI 2012
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347015/

Similar Items

Activation of the Silent Secondary Metabolite Production by Introducing Neomycin-Resistance in a Marine-Derived Penicillium purpurogenum G59
by: Wu, Chang-Jing, et al.
Published: (2015)

Rare Chromones from a Fungal Mutant of the Marine-Derived Penicillium purpurogenum G59
by: Xia, Ming-Wen, et al.
Published: (2015)

Purpurogemutantin and Purpurogemutantidin, New Drimenyl Cyclohexenone Derivatives Produced by a Mutant Obtained by Diethyl Sulfate Mutagenesis of a Marine-Derived Penicillium purpurogenum G59
by: Fang, Shi-Ming, et al.
Published: (2012)

Activation of Dormant Secondary Metabolite Production by Introducing Neomycin Resistance into the Deep-Sea Fungus, Aspergillus versicolor ZBY-3
by: Dong, Yuan, et al.
Published: (2014)

Improvement of submerged culture conditions to produce colorants by Penicillium purpurogenum
by: Santos-Ebinuma, Valéria Carvalho, et al.
Published: (2014)

Importance of the ammonia assimilation by Penicillium purpurogenum in amino derivative Monascus pigment, PP-V, production
by: Arai, Teppei, et al.
Published: (2013)

Thermostable saccharogenic amylase produced under submerged fermentation by filamentous fungus Penicillium purpurogenum
by: Silva, Tony Márcio, et al.
Published: (2011)

The relationship between the violet pigment PP-V production and intracellular ammonium level in Penicillium purpurogenum
by: Kojima, Ryo, et al.
Published: (2016)

Secondary Metabolites from Penicillium pinophilum SD-272, a Marine Sediment-Derived Fungus
by: Wang, Ming-Hui, et al.
Published: (2013)

Secondary Metabolites from Penicillium roqueforti, A Starter for the Production of Gorgonzola Cheese
by: Vallone, Lisa, et al.
Published: (2014)

Characterization of marine penicillium isolates and their antibiotics
by: Mohd.Noorzaifiqrudin, bin Khairol
Published: (2012)

Production of Bioactive Secondary Metabolites by Marine Vibrionaceae
by: Mansson, Maria, et al.
Published: (2011)

PTP1B Inhibitory and Anti-Inflammatory Effects of Secondary Metabolites Isolated from the Marine-Derived Fungus Penicillium sp. JF-55
by: Lee, Dong-Sung, et al.
Published: (2013)

Seven New and Two Known Lipopeptides as well as Five Known Polyketides: The Activated Production of Silent Metabolites in a Marine-Derived Fungus by Chemical Mutagenesis Strategy Using Diethyl Sulphate
by: Wu, Chang-Jing, et al.
Published: (2014)

Penicillinolide A: A New Anti-Inflammatory Metabolite from the Marine Fungus Penicillium sp. SF-5292
by: Lee, Dong-Sung, et al.
Published: (2013)

Epigenetic Modifiers Induce Bioactive Phenolic Metabolites in the Marine-Derived Fungus Penicillium brevicompactum
by: Seham S. El-Hawary, et al.
Published: (2018-07-01)

Deep sequencing of the microRNA expression in fall dormant and non-dormant alfalfa
by: Fan, Wenna, et al.
Published: (2014)

Identification and analysis of phosphorylation status of proteins in dormant terminal buds of poplar
by: Liu, Chang-Cai, et al.
Published: (2011)

Waking up dormant tumors
by: Tse, Joyce C, et al.
Published: (2011)

Diversity of Secondary Metabolites from Marine Bacillus Species: Chemistry and Biological Activity
by: Mondol, Muhammad Abdul Mojid, et al.
Published: (2013)

Metabolomic Tools for Secondary Metabolite Discovery from Marine Microbial Symbionts
by: Macintyre, Lynsey, et al.
Published: (2014)

Isolation and Characterization of Anti-Adenoviral Secondary Metabolites from Marine Actinobacteria
by: Strand, Mårten, et al.
Published: (2014)

Secondary Metabolites from the Soft Coral Sinularia arborea
by: Chen, Kuan-Hua, et al.
Published: (2013)

Three New and Eleven Known Unusual C25 Steroids: Activated Production of Silent Metabolites in a Marine-Derived Fungus by Chemical Mutagenesis Strategy using Diethyl Sulphate
by: Xia, Ming-Wen, et al.
Published: (2014)

Targeting Dormant Bacilli to Fight Tuberculosis
by: Fattorini, Lanfranco, et al.
Published: (2013)

Characterisation of marine penicillium isolates from Bako, Sarawak and their antibiotics
by: Chan, Olivia Jade Yin
Published: (2012)

Bioactive Compounds Produced by Strains of Penicillium and Talaromyces of Marine Origin
by: Nicoletti, Rosario, et al.
Published: (2016)

A New Record of Penicillium antarcticum from Marine Environments in Korea
by: Park, Myung Soo, et al.
Published: (2014)

Toxic Anterior Segment Syndrome following Phacoemulsification Secondary to Overdose of Intracameral Gentamicin
by: Koban, Yaran, et al.
Published: (2014)

Ergosterols from the Culture Broth of Marine Streptomyces anandii H41-59
by: Zhang, Yang-Mei, et al.
Published: (2016)

Comparative Transcriptome Analysis of the Less-Dormant Taiwanese Pear and the Dormant Japanese Pear during Winter Season
by: Takemura, Yoshihiro, et al.
Published: (2015)

The resemblance and disparity of gene expression in dormant and non-dormant seeds and crown buds of leafy spurge (Euphorbia esula)
by: Chao, Wun S, et al.
Published: (2014)

Biodegradation of gentamicin by bacterial consortia AMQD4 in synthetic medium and raw gentamicin sewage
by: Yuanwang Liu, et al.
Published: (2017-09-01)

Transcriptome analysis of dormant tomonts of the marine fish ectoparasitic ciliate Cryptocaryon irritans under low temperature
by: Yin, Fei, et al.
Published: (2016)

Shell-model calculations on 59Ni and 59CU
by: Sulaiman, M. Yusof, et al.
Published: (1981)

Genome sequencing and secondary metabolism of the postharvest pathogen Penicillium griseofulvum
by: Banani, Houda, et al.
Published: (2016)

Identifying and targeting dormant cells in acute myeloid leukaemia
by: Yu, N.
Published: (2016)

Trauma-associated growth of suspected dormant micrometastasis
by: El Saghir, Nagi S, et al.
Published: (2005)

Prospective Identification of Glioblastoma Cells Generating Dormant Tumors
by: Satchi-Fainaro, Ronit, et al.
Published: (2012)

Autochthonous and Dormant Cryptococcus gattii Infections in Europe
by: Hagen, Ferry, et al.
Published: (2012)